Publication | Closed Access
Deazaflavins as mediators in light-driven cytochrome P450 catalyzed hydroxylations
68
Citations
28
References
2009
Year
Expensive Nadph CofactorBiosynthesisBioorganic ChemistryEngineeringBiochemistryNatural SciencesBiocatalysisEnzyme CatalysisLight-driven Cytochrome P450Biochemical EngineeringSynthetic BiologySynthetic PhotochemistryChemical BiologyRedox BiologyBiomolecular Engineering
A light-driven deazaflavin-dependent direct enzyme regeneration system has been developed for a P450-BM3 catalyzed CH-activating hydroxylation, thereby avoiding the need for the expensive NADPH cofactor.
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