Muscarinic M3 receptors are coupled to two signal transduction pathways in rat submandibular cells

Pirenzepine distinguishes between different subclasses of muscarinic receptors

Rudolf Hammer, Christopher P. Berrie, N.J.M. Birdsall et al. · Nature · 1980 · 1.3K citations

Medicine, Neuroscience, Pharmacology +16

Selectivity of muscarinic antagonists in radioligand and in vivo experiments for the putative M1, M2 and M3 receptors.

H. N. Doods, M. J. Mathy, D. Davidesko et al. · Journal of Pharmacology and Experimental Therapeutics · 1987 · 442 citations

Medicine, Neuroscience, Pharmacology +17

An M2 Muscarinic Receptor Subtype Coupled to Both Adenylyl Cyclase and Phosphoinositide Turnover

Avi Ashkenazi, John Winslow, Ernest G. Peralta et al. · Science · 1987 · 397 citations

Medicine, Pharmacology, Cell Signaling +16

Phorbol ester induces desensitization of adenylate cyclase and phosphorylation of the beta-adrenergic receptor in turkey erythrocytes.

D J Kelleher, Jeffrey E. Pessin, Arnold E. Ruoho et al. · Proceedings of the National Academy of Sciences · 1984 · 234 citations · Full text

Life Sciences, Biochemistry, Pharmacology +15

Different tachykinin receptor subtypes are coupled to the phosphoinositide or cyclic AMP signal transduction pathways in rat submandibular cells

Adebayo Laniyonu, Eva Sliwinski-Lis, Norman Fleming · FEBS Letters · 1988 · 52 citations · Full text

Life Sciences, Cell Biology, Pharmacology +16