Genetic association analysis of GDF5 and ADAM12 for knee osteoarthritis

A functional polymorphism in the 5′ UTR of GDF5 is associated with susceptibility to osteoarthritis

Yoshinari Miyamoto, Akihiko Mabuchi, Dongquan Shi et al. · Nature Genetics · 2007 · 500 citations

Medicine, Genetics, Molecular Genetics +10

Genetic Factors in Generalized Osteo-Arthrosis

Jan Kellgren, J. S. Lawrence, F. Bier · Annals of the Rheumatic Diseases · 1963 · 302 citations

Medicine, Genetics, Orthopedic Surgery +9

An SNP in the 5′-UTR of GDF5 is associated with osteoarthritis susceptibility in Europeans and with in vivo differences in allelic expression in articular cartilage

Lorraine Southam, Julio A. Rodriguez‐Lopez, James M. Wilkins et al. · Human Molecular Genetics · 2007 · 218 citations

Life Sciences, Genetics, Molecular Genetics +13

Association study of candidate genes for the prevalence and progression of knee osteoarthritis

Ana M. Valdes, Deborah Hart, Karen A. Jones et al. · Arthritis & Rheumatism · 2004 · 180 citations

Medicine, Orthopaedic Surgery, Orthopedic Surgery +16

Reproducible genetic associations between candidate genes and clinical knee osteoarthritis in men and women

Ana M. Valdes, Mark Van Oene, Deborah Hart et al. · Arthritis & Rheumatism · 2006 · 176 citations

Life Sciences, Genetics, Molecular Genetics +13