Protective effect of the tachykinin NK2receptor antagonist nepadutant in acute rectocolitis induced by diluted acetic acid in guinea-pigs

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Life Sciences, Immunology, Physiology +12

Beneficial effects of local or systemic lidocaine in experimental colitis

Donna‐Marie McCafferty, Keith A. Sharkey, John L. Wallace · American Journal of Physiology-Gastrointestinal and Liver Physiology · 1994 · 133 citations

Medicine, Neurobiology, Pharmacology +17

Calcitonin Gene-Related Peptide Mediates the Protective Effect of Sensory Nerves in a Model of Colonic Injury

Max Reinshagen, Günther Flämig, Sabine Ernst et al. · Journal of Pharmacology and Experimental Therapeutics · 1998 · 123 citations

Medicine, Neuroscience, Pharmacology +17

MEN 11420 (Nepadutant), a novel glycosylated bicyclic peptide tachykinin NK₂ receptor antagonist

R.-M. Catalioto, Marco Criscuoli, Paola Cucchi et al. · British Journal of Pharmacology · 1998 · 94 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +15

Role of tachykinin NK2 receptors in normal and altered rectal sensitivity in rats

Marc-Etienne Toulouse, Anne-Marie Coelho, Jean Fioramonti et al. · British Journal of Pharmacology · 2000 · 64 citations · Full text

Medicine, Neurobiology, Pharmacology +16