Concepedia

Pharmacokinetics and Acid‐suppressive Effects of Esomeprazole in Infants 1–24 Months Old With Symptoms of Gastroesophageal Reflux Disease

Taher Omari, Geoffrey P. Davidson, Patrik Bondarov, Emma Nauclér, Catarina Nilsson, Per Lundborg

Journal of Pediatric Gastroenterology and Nutrition · 2007 · 60 citations · 26 references

DOI

Abstract

Oral treatment with esomeprazole 0.25 mg/kg and 1 mg/kg was well tolerated and provided dose-related acid suppression, dose-related exposure to esomeprazole, and decreased esophageal acid exposure in infants 1-24 months old with GERD.

References

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COMPARISON OF INHIBITORY EFFECTS OF THE PROTON PUMP-INHIBITING DRUGS OMEPRAZOLE, ESOMEPRAZOLE, LANSOPRAZOLE, PANTOPRAZOLE, AND RABEPRAZOLE ON HUMAN CYTOCHROME P450 ACTIVITIES

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