Secretion of bioactive hepcidin-25 by liver cells correlates with its gene transcription and points towards synergism between iron and inflammation signaling pathways

A new mathematical model for relative quantification in real-time RT-PCR

Michael W. Pfaffl · Nucleic Acids Research · 2001 · 34.9K citations · Full text

Life Sciences, Molecular Biology, Gene Expression +12

Hepcidin Regulates Cellular Iron Efflux by Binding to Ferroportin and Inducing Its Internalization

Elizabeta Nemeth, Marie S. Tuttle, Julie Powelson et al. · Science · 2004 · 4.8K citations

Medicine, Cell Biology, Physiology +17

Locating proteins in the cell using TargetP, SignalP and related tools

Olof Emanuelsson, Søren Brunak, Gunnar von Heijne et al. · Nature Protocols · 2007 · 3.2K citations

Life Sciences, Bioinformatics, Molecular Biology +11

IL-6 mediates hypoferremia of inflammation by inducing the synthesis of the iron regulatory hormone hepcidin

Elizabeta Nemeth, Seth Rivera, Victoria Gabayan et al. · Journal of Clinical Investigation · 2004 · 2.2K citations

Life Sciences, Immunology, Pathology +17

Hepcidin, a Urinary Antimicrobial Peptide Synthesized in the Liver

Christina H. Park, Erika V. Valore, Alan J. Waring et al. · Journal of Biological Chemistry · 2001 · 2.2K citations · Full text

Life Sciences, Microbiology, Molecular Biology +13