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Nonspecific Amine Immobilization of Ligand Can Be a Potential Source of Error in BIAcore Binding Experiments and May Reduce Binding Affinities

EngineeringBiochemistryMedicinePharmacologyBiacore Binding ExperimentsMechanism Of ActionLigand Can BeMolecular RecognitionMolecular DockingMolecular ModelingNonspecific Amine ImmobilizationDrug Discovery