Autoantibodies against malondialdehyde-modified lipoprotein(a) in antiphospholipid syndrome

Abstract

We report for the first time the existence of autoantibodies against MDA-Lp(a). The presence of antibodies reacting not only against MDA-LDL but also against MDA-Lp(a) supports the hypothesis of a role for oxidative phenomena in the pathogenesis of APS and atherosclerosis.