Chemical Communications · 2010 · 115 citations · 29 references
Materials ScienceAmorphous Calcium PhosphateEngineeringMineral FormationHydroxyapatiteMicroscopyBiomineralizationSitu Extinction DetectionCalcium AluminateBioceramicOsteoporosisBiomedical EngineeringCrystallographySimulated Physiological FluidMedicineOrthopaedic SurgeryBiophysicsUltrastructure
The process from the amorphous calcium phosphate phase to the hydroxyapatite (HAP) crystalline phase has been captured in a simulated physiological fluid by combining in situ extinction detection and ex situ electronic microscopy. The results reveal the secret of the phase transformation and orientation controls during the initial stage of mineral formation.
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