Stealth Rare Earth Oxide Nanodiscs for Magnetic Resonance Imaging

Abstract

Configuring RE2O3 nanocrystals with pseudo-2D morphologies confers substantive gains in relaxivities over equivalent spherical counterparts. The most promising arises from Gd2O3 whose ionic transverse and longitudinal relaxivities were as high as r1 = 12.7 mM−1 s−1 and r2 = 17.2 mM−1 s−1 (dispersed in H2O, T = 37 °C & B0 = 1.41 T), pointing to new opportunities to achieve high contrast MRI while concomitantly affording longer half-life potential in vivo. Detailed facts of importance to specialist readers are published as ”Supporting Information”. Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.