Steric control of DNA interstrand cross-link sites of trans platinum complexes: specificity can be dictated by planar nonleaving groups

[57] Sequencing end-labeled DNA with base-specific chemical cleavages

Allan M. Maxam, Walter Gilbert · Methods in enzymology on CD-ROM/Methods in enzymology · 1980 · 14.7K citations

Pharmacy, Biotechnology, Molecular Biology +13

Adducts of the antitumor drug cis-diamminedichloroplatinum(II) with DNA: formation, identification, and quantitation

Anne Marie J. Fichtinger-Schepman, J. L. VAN DER VEER, Jeroen H. J. Den Hartog et al. · Biochemistry · 1985 · 1K citations

Medicine, Oncology, Pharmacology +8

Platinum-195 NMR kinetic and mechanistic studies of cis- and trans-diamminedichloroplatinum(II) binding to DNA

Daniel P. Bancroft, Christopher A. Lepre, Stephen J. Lippard · Journal of the American Chemical Society · 1990 · 478 citations

Natural Sciences, Biochemistry, Chemistry +8

DNA interstrand cross-links of trans-diamminedichloroplatinum(II) are preferentially formed between guanine and complementary cytosine residues.

Viktor Brabec, M. Leng · Proceedings of the National Academy of Sciences · 1993 · 245 citations

Pharmacy, Molecular Biology, Nucleic Acid Biochemistry +14

Activation of the trans geometry in platinum antitumor complexes. Synthesis, characterization, and biological activity of complexes with the planar ligands pyridine, N-methylimidazole, thiazole, and quinoline. Crystal and molecular structure of trans-dichlorobis(thiazole)platinum(II)

Marijo Van Beusichem, Nicholas P. Farrell · Inorganic Chemistry · 1992 · 233 citations

Natural Sciences, Chemistry, Medicinal Chemistry +12