Runx2: A novel oncogenic effector revealed by in vivo complementation and retroviral tagging

Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

Lawrence A. Donehower, Michele Harvey, Betty L. Slagle et al. · Nature · 1992 · 4.7K citations

Medicine, Cancer Biology, Molecular Genetics +14

Osf2/Cbfa1: A Transcriptional Activator of Osteoblast Differentiation

Patricia Ducy, Rui Zhang, Valérie Geoffroy et al. · Cell · 1997 · 4.3K citations · Full text

Medicine, Genetics, Molecular Biology +11

Targeted Disruption of Results in a Complete Lack of Bone Formation owing to Maturational Arrest of Osteoblasts

Toshihisa Komori, Hideshi Yagi, Shogo Nomura et al. · Cell · 1997 · 4.2K citations · Full text

Medicine, Developmental Biology, Orthopedic Surgery +16

Cbfa1, a Candidate Gene for Cleidocranial Dysplasia Syndrome, Is Essential for Osteoblast Differentiation and Bone Development

Florian Otto, Anders Thornell, Tessa Crompton et al. · Cell · 1997 · 2.8K citations · Full text

Dentistry, Genetics, Molecular Genetics +14

AML1, the Target of Multiple Chromosomal Translocations in Human Leukemia, Is Essential for Normal Fetal Liver Hematopoiesis

Tsukasa Okuda, Jan M. van Deursen, Scott W. Hiebert et al. · Cell · 1996 · 1.9K citations · Full text

Life Sciences, Genetics, Molecular Biology +16