Catalytic Asymmetric Diamination of Conjugated Dienes and Triene

Abstract

This paper describes a catalytic asymmetric diamination process using di- tert -butyldiaziridinone as nitrogen source with catalyst generated from Pd 2 (dba) 3 and chiral phosphorus amidite ligand. A wide variety of conjugated dienes and triene can be effectively diaminated in good yields with high regio-, diastereo-, and enantioselectivities.