Aberrant promoter methylation and silencing of the RASSF1A gene in pediatric tumors and cell lines

Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands.

James G. Herman, Jeremy R. Graff, Sanna Myöhänen et al. · Proceedings of the National Academy of Sciences · 1996 · 5.7K citations

Life Sciences, Genetics, Molecular Biology +17

A gene hypermethylation profile of human cancer.

Manel Esteller, Paul G. Corn, Stephen B. Baylin et al. · PubMed · 2001 · 2K citations

Medicine, Molecular Biology, Oncology +17

Alterations in DNA Methylation: A Fundamental Aspect of Neoplasia

Stephen B. Baylln, James G. Herman, Jeremy R. Graff et al. · Advances in cancer research · 1997 · 1.9K citations

Medicine, Genetics, Oncology +14

Inactivation of the DNA repair gene O6-methylguanine-DNA methyltransferase by promoter hypermethylation is a common event in primary human neoplasia.

Manel Esteller, Stanley R. Hamilton, P C Burger et al. · PubMed · 1999 · 1.3K citations

Medicine, Genetics, Oncology +16

Epigenetic inactivation of a RAS association domain family protein from the lung tumour suppressor locus 3p21.3

Reinhard Dammann, Chun Li, Jung‐Hoon Yoon et al. · Nature Genetics · 2000 · 1.1K citations

Medicine, Genetics, Molecular Genetics +15