Comparative transfection studies of human ovarian carcinoma cellsin vitro,ex vivo andin vivo with poly(2-(dimethylamino)ethyl methacrylate)-based polyplexes

Abstract

P(DMAEMA) is an efficient transfectant in vitro and ex vivo. However, transfected cells were not detected in vivo which may be caused by a negative influence of components of the ascites fluid.