ImmunoSPECT and ImmunoPET of IGF-1R Expression with the Radiolabeled Antibody R1507 in a Triple-Negative Breast Cancer Model

Sandra Heskamp, Hanneke W.M. van Laarhoven, Janneke D.M. Molkenboer‐Kuenen, Gerben M. Franssen, Yvonne M.H. Versleijen‐Jonkers, Wim J.G. Oyen, Winette T.A. van der Graaf, Otto C. Boerman

Journal of Nuclear Medicine · 2010 · 92 citations · 37 references

DOIFull text

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Abstract

(111)In-R1507 and (89)Zr-R1507 are new tracers to noninvasively determine IGF-1R expression in vivo in breast cancer xenografts using SPECT and PET. In the future, these techniques may enable patient selection for IGF-1R-targeted therapy.

References

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