Sox9 directly promotes Bapx1 gene expression to repress Runx2 in chondrocytes

Targeted Disruption of Results in a Complete Lack of Bone Formation owing to Maturational Arrest of Osteoblasts

Toshihisa Komori, Hideshi Yagi, Shogo Nomura et al. · Cell · 1997 · 4.2K citations · Full text

Medicine, Developmental Biology, Orthopedic Surgery +16

Cbfa1, a Candidate Gene for Cleidocranial Dysplasia Syndrome, Is Essential for Osteoblast Differentiation and Bone Development

Florian Otto, Anders Thornell, Tessa Crompton et al. · Cell · 1997 · 2.8K citations · Full text

Dentistry, Genetics, Molecular Genetics +14

Sox9 is required for cartilage formation

Weimin Bi, Jian Min Deng, Zhaoping Zhang et al. · Nature Genetics · 1999 · 1.8K citations

Life Sciences, Cell Biology, Developmental Biology +10

The transcription factor Sox9 has essential roles in successive steps of the chondrocyte differentiation pathway and is required for expression of <i>Sox5</i> and <i>Sox6</i>

Haruhiko Akiyama, Marie‐Christine Chaboissier, James F. Martin et al. · Genes & Development · 2002 · 1.7K citations · Full text

Life Sciences, Developmental Biology, Genetics +17

SOX9 Is a Potent Activator of the Chondrocyte-Specific Enhancer of the Proα1(II) Collagen Gene

Véronique Lefebvre, Wendong Huang, Vincent R. Harley et al. · Molecular and Cellular Biology · 1997 · 1.1K citations · Full text

Life Sciences, Genetics, Molecular Genetics +11