Efficient Intermolecular Iron-Catalyzed Amidation of C−H Bonds in the Presence of <i>N</i>-Bromosuccinimide

Abstract

We have developed an efficient, inexpensive, and air-stable catalyst/oxidant (FeCl2/NBS) system that could efficiently promote amidation of benzylic sp3 C-H bonds in ethyl acetate under mild conditions.