A combination of two novel alpha globin variants Hb Bridlington (<i>HBA1</i>) and Hb Taybe (<i>HBA2</i>) resulting in severe hemolysis, pulmonary hypertension, and death

Abstract

Splenectomy was not clearly beneficial and may have contributed to the development of pulmonary hypertension. The case favors a cautious approach when considering splenectomy for patients with Hb Taybe.