Synthesis and evaluation of a backbone biodegradable multiblock HPMA copolymer nanocarrier for the systemic delivery of paclitaxel

Hypersensitivity reactions from taxol.

R B Weiss, Ross C. Donehower, Peter H. Wiernik et al. · Journal of Clinical Oncology · 1990 · 1.2K citations

Drug Hypersensitivity, Oncology, Allergy +14

Water-Soluble Polymers. 81. Direct Synthesis of Hydrophilic Styrenic-Based Homopolymers and Block Copolymers in Aqueous Solution via RAFT

Yoshiro Mitsukami, Michael S. Donovan, Andrew B. Lowe et al. · Macromolecules · 2001 · 716 citations

Engineering, Responsive Polymers, Chemistry +18

Paclitaxel-loaded PEGylated PLGA-based nanoparticles: In vitro and in vivo evaluation

Fabienne Danhier, Nathalie Lecouturier, Benoı̂t Vroman et al. · Journal of Controlled Release · 2008 · 593 citations

Nanoparticles, Nanomedicine, Engineering +7

Effect of molecular weight (M_<i>w</i>) of<i>N</i>‐(2‐hydroxypropyl)methacrylamide copolymers on body distribution and rate of excretion after subcutaneous, intraperitoneal, and intravenous administration to rats

Leonard W. Seymour, Ruth Duncan, J. Strohalm et al. · Journal of Biomedical Materials Research · 1987 · 428 citations

Nonlinear pharmacokinetics of paclitaxel in mice results from the pharmaceutical vehicle Cremophor EL.

Alex Sparreboom, Olaf van Tellingen, W J Nooijen et al. · PubMed · 1996 · 315 citations

Nonlinear Pharmacokinetics, Medicinal Chemistry, Pharmaceutical Science +14