(Trimethylsilyl)ethoxyacetylene. An Effective Reagent for Mild Dehydrative Condensation of Carboxylic Acids and<i>H</i>-Acidic Materials

Abstract

(Trimethylsilyl)ethoxyacetylene, a stable and easy to handle dehydrating reagent, is quite effective for the title condensation to prepare esterlactone-, lactam-, and peptide-linkages under mild conditions.