Production of single- and double-strand breaks in plasmid dna by ozone

A rapid boiling method for the preparation of bacterial plasmids

David S. Holmes, Michael E. Quigley · Analytical Biochemistry · 1981 · 3.3K citations

Life Sciences, Microbiology, Molecular Biology +13

Nonchromosomal Antibiotic Resistance in Bacteria: Genetic Transformation of <i>Escherichia coli</i> by R-Factor DNA

Stanley N. Cohen, Annie Chang, Leslie Hsu · Proceedings of the National Academy of Sciences · 1972 · 2.7K citations

Life Sciences, Genetics, Microbiology +15

Trans-complementable copy-number mutants of plasmid ColE1

A Twigg, David J. Sherratt · Nature · 1980 · 972 citations

Life Sciences, Genetics, Molecular Genetics +14

Random subcloning of sonicated DNA: Application to shotgun DNA sequence analysis

Prescott L. Deininger · Analytical Biochemistry · 1983 · 600 citations

Life Sciences, Genetics, Molecular Biology +12

Ozonation of Water: Role of Hydroxyl Radicals as Oxidizing Intermediates

J. Hoigné, H. Bader · Science · 1975 · 203 citations

Natural Sciences, Biochemistry, Chemistry +16