Journal of Occupational and Environmental Medicine · 2004 · 35 citations · 17 references
PharmacyToxicologyOccupational ToxicologyRadiation ProtectionRadiation SafetyDecontamination ProceduresExposure AssessmentExposure MonitoringOccupational Radiation SafetyRadiation HealthRadiation Risk AssessmentBeryllium Exposure AssessmentBeryllium Lymphocyte Proliferation TestingBeryllium Risk AssessmentBeryllium SensitizationBeryllium Workplace SurveillanceChronic Beryllium DiseaseCleanupOccupational Beryllium Exposure
Despite increasing need to remediate beryllium-contaminated buildings in industry, little is known about the magnitude of risk associated with beryllium abatement or the merits of beryllium medical surveillance for cleanup workers. We examined beryllium lymphocyte proliferation tests and reviewed medical evaluations on workers at a nuclear weapons facility during the process of decontamination and decommissioning. Of 2,221 workers, 19 (0.8%) were beryllium sensitized based on two or more abnormal beryllium lymphocyte proliferation tests. Eight of 19 sensitized individuals underwent full clinical evaluation, of whom two were diagnosed with chronic beryllium disease (CBD). Notably, seven beryllium sensitized and CBD cases were hired after the start of cleanup operations. Beryllium medical surveillance detects sensitization and CBD in cleanup workers. Exposure controls and medical surveillance need to be 'broad-based' to include all cleanup workers involved in beryllium-contaminated building remediation.
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Epidemiology of Beryllium Sensitization and Disease in Nuclear Workers
Kathleen Kreiss, Margaret M. Mroz, Boguang Zhen et al. · American Review of Respiratory Disease · 1993 · 201 citations
Medicine, Immunology, Pathology +17