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Enantioselective Synthesis of α‐Methyl‐α‐aminocarboxylic Acids by Alkylation of the Lactim Ether of <i>cyclo</i>‐(<scp>L</scp>‐Ala‐<scp>L</scp>‐Ala)
79
Citations
4
References
1979
Year
Chiral Auxiliary AgentPermit RecoveryBiosynthesisEngineeringBiochemistryNatural SciencesGive YieldsPeptide SynthesisOrganic ChemistryStereoselective SynthesisChemistryα‐Methyl‐α‐aminocarboxylic AcidsNatural Product SynthesisAsymmetric CatalysisSynthetic ChemistryEnantioselective SynthesisBiomolecular EngineeringLactim Ether
Preparatively valuable asymmetric amino acid syntheses must be simple to carry out, give yields of >90%, and, where appropriate, permit recovery of the chiral auxiliary agent. These demands are met by the new synthesis via cyclo-(L-Ala-L-Ala).
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