Concepedia

Cytotoxicity of 1,2-diacetylbenzene in human neuroblastoma SHSY5Y cells is mediated by oxidative stress

Min Sun Kim, Min Sun Kim, Min Kyeong Kim, Min Kyeong Kim, Kwang Seok Kim, Jae Heun Chung, So Jung Kim, Jung Hye Kim, Jae‐Ryong Kim, Jaewon Lee,

Toxicology · 2007 · 25 citations · 26 references

DOI

Concepts

References

26

Evidence of ROS generation by mitochondria in cells with impaired electron transport chain and mitochondrial DNA damage

Hiroko P. Indo, Mercy M. Davidson, Hsiu‐Chuan Yen et al. · Mitochondrion · 2006 · 524 citations

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The effect of aliphatic, naphthenic, and aromatic hydrocarbons on production of reactive oxygen species and reactive nitrogen species in rat brain synaptosome fraction: the involvement of calcium, nitric oxide synthase, mitochondria, and phospholipase A11Abbreviations: BIM, bisindolylmaleimide; [Ca2+]i, concentration of intracellular calcium; ChAT, cholin acetyltransferase; CSA, cyclosporin A; DCF, 2′,7′-dichlorofluorescein; H2DCF-DA, 2′,7′-dichlorodihydrofluorescin diacetate; DEDA, dimethyleicosadienoic acid; ERK, extracellular signal-regulated kinases; Fura-2 AM, 5-oxazolecarboxylic acid, 2-(6-(bis(2-((acetyloxy)methoxy)-2-oxoethyl)amino)-5-(2-(bis(2-((acetyloxy)methoxy)-2oxoethyl)amino)-5-methylphenoxy)ethoxy)-2-benzofuranyl)-, (acetyloxy) methyl ester; GABA-T, gamma-aminobutyric acid transaminase; HBSS, Hanks’ balanced salt solution; La3+, lanthanum; MAPK, mitogen-activated protein kinase; MeHg, methyl mercury; MEK, extracellular signal-regulated protein kinase; MeOH, methanol; MTP, mitochondrial permeability transition pore; L-NAME, Nω-nitro-l-arginine methyl ester; NO·, nitrogen oxide; NOS, NO· synthase; O2·−, superoxide; PLA2, phospholipase A2; PKC, protein kinase C; RNS, reactive nitrogen species; ROS, reactive oxygen species; SOD, superoxide dismutase; TMB, 1,2,4-trimethylbenzene; TMCH, 1,2,4-trimethylcyclohexane; and U73122, 1-(6-[17beta-3-methoxyestra- 1,3,5(10)-trien- 17-yl]-aminohexyl)- 1H-pyrrole-2,5-dione.

Oddvar Myhre, Frode Fonnum · Biochemical Pharmacology · 2001 · 79 citations

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Residue-Specific Adduction of Tubulin by 4-Hydroxynonenal and 4-Oxononenal Causes Cross-Linking and Inhibits Polymerization

Benjamin J. Stewart, Jonathan A. Doorn, Dennis R. Petersen · Chemical Research in Toxicology · 2007 · 76 citations

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The neurotoxins 2,5‐hexanedione and acrylamide promote aggregation of intermediate filaments in cultured fibroblasts

Heather D. Durham, Sérgio D.J. Pena, Stirling Carpenter · Muscle & Nerve · 1983 · 76 citations

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Effect of aldehydes derived from oxidative deamination and oxidative stress on β-amyloid aggregation; pathological implications to Alzheimer’s disease

Kuei-Jung Chen, Michael Kazachkov, P. H. Yu · Journal of Neural Transmission · 2007 · 75 citations

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