Concepedia

Two free radical routes for the preparation of novel difluoromethylene-linked serine-O-glycopeptide analogues

Timothée F. Herpin, William B. Motherwell, Jean‐Marc Weibel

Chemical Communications · 1997 · 48 citations · 13 references

DOI

Concepts

Abstract

The first examples of gem-difluoromethylene-linked analogues of serine-derived glycopeptides have been prepared in a highly stereoselective manner using two complementary free radical chain reactions.

References

13

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The Stereoselectivity of Intermolecular Free Radical Reactions [New Synthetic Methods (78)]

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Preparation of enantiomerically pure protected 4-oxo .alpha.-amino acids and 3-aryl .alpha.-amino acids from serine

Richard F. W. Jackson, Neil Wishart, Anthony Wood et al. · The Journal of Organic Chemistry · 1992 · 190 citations

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Glycosyl .alpha.-amino acids via stereocontrolled buildup of a penaldic acid equivalent. A novel synthetic approach to the nucleosidic component of the polyoxins and related substances

Philip Garner, Jung Min Park · The Journal of Organic Chemistry · 1990 · 98 citations

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Manipulation of the cabboxyl groups of α-amino-acids and peptides using radical chemistry based on esters of -hydroxy-2-thiopyridone

D. H. R. BARTON, Yolande Hervé, Pierre Potìer et al. · Tetrahedron · 1988 · 95 citations

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