Voltage-dependent action of valproate on potassium channels in frog node of Ranvier

A quantitative description of membrane current and its application to conduction and excitation in nerve

A. L. Hodgkin, A. F. Huxley · The Journal of Physiology · 1952 · 22.9K citations · Full text

Hyperpolarization (Biology), Neurophysiology, Physiology +11

Negative surface charge near sodium channels of nerve: divalent ions, monovalent ions, and pH

Bertil Hille, Ann M. Woodhull, Bert I. Shapiro · Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 1975 · 594 citations

Extracellular potassium activity during epileptogenesis

William J. Moody, Kin J. Futamachi, David A. Prince · Experimental Neurology · 1974 · 290 citations

Hypertonicity, Electrolyte Disorder, Developmental Biology +8

Sodium valproate, but not ethosuximide, produces use- and voltage-dependent limitation of high frequency repetitive firing of action potentials of mouse central neurons in cell culture.

Michael J. McLean, Robert L. Macdonald · Journal of Pharmacology and Experimental Therapeutics · 1986 · 273 citations

Quantitative description of sodium currents in myelinated nerve fibres of <i>Xenopus laevis</i>

B. Frankenhaeuser · The Journal of Physiology · 1960 · 222 citations · Full text

Synaptic Transmission, Sodium Currents, Neurotransmission +18