Functional characterization of malignant hyperthermia-associated RyR1 mutations in exon 44, using the human myotube model

A new generation of Ca2+ indicators with greatly improved fluorescence properties.

Grzegorz Grynkiewicz, Martin Poenie, Roger Y. Tsien · Journal of Biological Chemistry · 1985 · 21.7K citations · Full text

Ryanodine receptor gene is a candidate for predisposition to malignant hyperthermia

David H. MacLennan, Catherine Duff, Francesco Zorzato et al. · Nature · 1990 · 524 citations

Molecular Physiology, Signal Transduction, Hyperthermia +5

A PROTOCOL FOR THE INVESTIGATION OF MALIGNANT HYPERPYREXIA (MH) SUSCEPTIBILITY

British Journal of Anaesthesia · 1984 · 443 citations · Full text

Diagnosis, Pathology, Neuropathology +2

Localization of the malignant hyperthermia susceptibility locus to human chromosome 19ql2–13.2

Tommie V. McCarthy, John Healy, J.J.A. Heffron et al. · Nature · 1990 · 372 citations

Hyperthermia, Cytogenetics, Genetic Disorder +10

In vitro contracture test for diagnosis of malignant hyperthermia following the protocol of the European MH Group: Results of testing patients surviving fulminant MH and unrelated low‐risk subjects

Helle Ørding, Virginia Brancadoro, Santolo Cozzolino et al. · Acta Anaesthesiologica Scandinavica · 1997 · 295 citations