Efficacy and safety of ganirelix acetate versus leuprolide acetate in women undergoing controlled ovarian hyperstimulation

A double-blind, randomized, dose-finding study to assess the efficacy of the gonadotrophin-releasing hormone antagonist ganirelix (Org 37462) to prevent premature luteinizing hormone surges in women undergoing ovarian stimulation with recombinant follicle stimulating hormone (Puregon). The ganirelix dose-finding study group

Human Reproduction · 1998 · 293 citations · Full text

Pharmacy, Endocrinology, Pharmacology +17

Pharmacokinetic and pharmacodynamic characteristics of ganirelix (Antagon/Orgalutran ). part II. dose-proportionality and gonadotropin suppression after multiple doses of ganirelix in healthy female volunteers

Janine Oberyé, Bernadette Mannaerts, J. Huisman et al. · Fertility and Sterility · 1999 · 98 citations

Medicine, Pharmacokinetics, Pharmacology +10

Pharmacokinetic and pharmacodynamic characteristics of ganirelix (Antagon/Orgalutran ). part I. absolute bioavailability of 0.25 mg of ganirelix after a single subcutaneous injection in healthy female volunteers

Janine Oberyé, Bernadette Mannaerts, H J Kleijn et al. · Fertility and Sterility · 1999 · 70 citations

Pharmacy, Pharmacokinetics, Pharmacology +12

Neuropsychologic dysfunction in women following leuprolide acetate induction of hypoestrogenism

Nils R. Varney, Craig H. Syrop, Cynthia S. Kubu et al. · Journal of Assisted Reproduction and Genetics · 1993 · 56 citations

Medicine, Endocrinology, Psychiatry +13