Glomangiopericytoma: An uncommon sinonasal perivascular tumor with particular characteristics

Abstract

Glomangiopericytoma, sinonasal type hemangiopericytoma, is a rare sinonasal neoplasm with a perivascular myoid phenotype, and accounts for less than 0.5% of all sinonasal tumors. It is considered a distinct entity and differs from conventional soft-tissue hemangiopericytoma in location, clinical and histopathologic features. Glomangiopericytoma is a borderline low malignancy tumor with a good prognosis after complete surgical resection. We present the case of a 19-year-old girl presented with a progressive nasal obstruction, anosmia and epistaxis. Rhinoscopic examination and imaging studies showed a mass occupying the left nasal cavity without bone destruction. The tumor was removed successfully by endoscopic endonasal surgery. The anatomopathology examination with immunohistochemistry confirmed the diagnosis of glomangiopericytoma. In the light of this observation and a literature review, clinical aspects, histological characteristics, therapeutic principles and prognosis of this tumor will be discussed.