Concepedia

Continuous‐Flow CH Borylation of Arene Derivatives

Tsuyoshi Tagata, Mayumi Nishida, Atsushi Nishida

Advanced Synthesis & Catalysis · 2010 · 26 citations · 39 references

DOI

Concepts

Abstract

Abstract A new continuous‐flow system for CH borylation has been developed. An insoluble catalyst prepared from chloro(1,5‐cyclooctadien)iridium(I) dimer and 2,2′‐bipyridine‐4,4′‐dicarboxylic acid in the presence of bis(pinacolato)diboron exhibited high reactivity under continuous‐flow processing without the loss of expensive iridium metal.

References

39

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A Stoichiometric Aromatic CH Borylation Catalyzed by Iridium( <scp>I</scp> )/2,2′‐Bipyridine Complexes at Room Temperature

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Multistep Continuous‐Flow Microchemical Synthesis Involving Multiple Reactions and Separations

Hemantkumar R. Sahoo, Jason G. Kralj, Klavs F. Jensen · Angewandte Chemie International Edition · 2007 · 396 citations

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Iridium-catalyzed C–H coupling reaction of heteroaromatic compounds with bis(pinacolato)diboron: regioselective synthesis of heteroarylboronates

Jun Takagi, Kazuaki Sato, John F. Hartwig et al. · Tetrahedron Letters · 2002 · 359 citations · Full text

, , +14