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A new approach to the synthesis of the prostanoids
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1976
Year
Combinatorial ChemistryBioorganic ChemistryEngineeringBiochemistryHeterocyclicNatural SciencesPga1-type CompoundsFragments LeavesNew ApproachOrganic ChemistrySynthetic ChemistryChemistryHeterocycle ChemistryNatural Product SynthesisEnone SystemEnantioselective SynthesisBiomolecular Engineering
A short, simple synthesis of PGA1-type compounds, wherein the assembly of fragments leaves scope for variations at a later stage is described; this method involves the use of a bicyclo[2.2.1]heptene as a protecting group and precursor of the conjugated enone system, present in the final products.