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Transmission of Frequent Impulse Series in Sensory Nerves of Patients with Alcoholic Polyneuropathy
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1974
Year
Peripheral Nerve InjuryNeuropathic PainAction Potential AmplitudesPeripheral NerveFrequent Impulse SeriesSensory Nerve FibresPeripheral NervesPeripheral Nervous SystemSocial SciencesKinesiologyNeurologyNeuropathologySensory NervesSensationRehabilitationNervous SystemNeurophysiologyNeuroanatomyAlcoholic PolyneuropathyNeuroscienceElectrophysiologyCentral Nervous SystemConduction VelocityMedicine
Conduction velocity and action potential amplitudes of sensory nerve fibres have been reported to be slightly reduced in patients with alcoholic polyneuropathy. These statistical differences between patients and control groups are not helpful in the diagnosis of individual cases. Sural and median sensory nerve fibres of 8 alcoholics were examined, the results were compared with those of a group of 19 volunteers. By applying trains of frequent stimuli and evaluation of the latency and amplitude of the tenth response in each train, abnormal function could be demonstrated even in nerves with apparently normal conduction velocities and amplitudes on conventional examination. In discussing the results, histological findings are taken into consideration.