Increased apoptotic neuronal cell death and cognitive impairment at early phase after traumatic brain injury in aged rats

Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death

David M. Hockenbery, Gabriel Núñez, Curt Milliman et al. · Nature · 1990 · 3.8K citations

Life Sciences, Cell Biology, Molecular Biology +13

Overexpression of BCL-2 in transgenic mice protects neurons from naturally occurring cell death and experimental ischemia

Jean‐Claude Martinou, Michel Dubois‐Dauphin, Julie K. Staple et al. · Neuron · 1994 · 1.1K citations

Life Sciences, Neurobiology, Neuroscience +16

Outcome from head injury related to patient' age

Thomas G. Luerssen, M R Klauber, Lawrence F. Marshall · Journal of neurosurgery · 1988 · 531 citations

Medicine, Neurological Surgery, Pediatrics +15

Mitochondrial Dysfunction and Calcium Perturbation Induced by Traumatic Brain Injury

Ye Xiong, Qian Gu, P. L. Peterson et al. · Journal of Neurotrauma · 1997 · 447 citations

Life Sciences, Neurobiology, Neuroscience +17

Impaired mitochondrial function, oxidative stress and altered antioxidant enzyme activities following traumatic spinal cord injury

Robert D. Azbill, Xiaojun Mu, Annadora J. Bruce‐Keller et al. · Brain Research · 1997 · 311 citations

Medicine, Neurobiology, Neuroscience +16