Concepedia

Investigation of low viability in sparged bioreactor CHO cell cultures points to variability in the Pluronic F-68 shear protecting component of cell culture media

Pani A. Apostolidis, Alice Tseng, Marie-Eve Koziol, Michael J. Betenbaugh, Barbara Chiang

Biochemical Engineering Journal · 2015 · 19 citations · 32 references

DOI

Concepts

References

32

Physical mechanisms of cell damage in microcarrier cell culture bioreactors

Robert Cherry, Eleftherios T. Papoutsakis · Biotechnology and Bioengineering · 1988 · 246 citations

, , +17

Damage mechanisms of suspended animal cells in agitated bioreactors with and without bubble entrainment

Kurt T. Kunas, Eleftherios T. Papoutsakis · Biotechnology and Bioengineering · 1990 · 243 citations

, , +17

Sparged Animal Cell Bioreactors: Mechanism of Cell Damage and Pluronic F‐68 Protection

David W. Murhammer, Charles F. Goochee · Biotechnology Progress · 1990 · 172 citations

, , +15

The potential of hydrodynamic damage to animal cells of industrial relevance: current understanding

Weiwei Hu, Claudia Berdugo, Jeffrey J. Chalmers · Cytotechnology · 2011 · 146 citations · Full text

, , +9

Microscopic Visualization of Insect Cell‐Bubble Interactions. II: The Bubble Film and Bubble Rupture

Jeffrey J. Chalmers, Farshad Bavarian · Biotechnology Progress · 1991 · 135 citations

, , +13