Concepedia

Complete elimination of reflux symptoms does not guarantee normalization of intraesophageal acid reflux in patients with Barrett's esophagus

The American Journal of Gastroenterology · 1998 · 156 citations · 20 references

Abstract

Complete symptom eradication with lansoprazole (15-30 mg daily) in patients with Barrett's esophagus does not guarantee normalization of intraesophageal pH profile. If the goal of therapy in such patients is to achieve complete intraesophageal acid suppression, 24-h ambulatory esophageal pH monitoring should be performed to titrate therapy.

References

20

Duodenogastroesophageal reflux: Relationship to pH and importance in Barrett's esophagus

Gregory Champion, Joel E. Richter, Michael F. Vaezi et al. · Gastroenterology · 1994 · 461 citations · Full text

Duodenogastroesophageal Reflux, Esophageal Cancer, Esophagus +2

The Relation of Gastroesophageal Reflux Disease and Its Treatment to Adenocarcinomas of the Esophagus and Gastric Cardia

Wong-Ho Chow · JAMA · 1995 · 365 citations

Dynamic effects of acid on Barrett's esophagus. An ex vivo proliferation and differentiation model.

Rebecca C. Fitzgerald, M. Bishr Omary, George Triadafilopoulos · Journal of Clinical Investigation · 1996 · 318 citations · Full text

Ex Vivo Proliferation, Esophageal Cancer, Dynamic Effects +13

Normal 24-Hr ambulatory esophageal pH values

Joel E. Richter, Laurence A. Bradley, Tom R. DeMeester et al. · Digestive Diseases and Sciences · 1992 · 317 citations

Esophagus, Esophageal Cancer, Medicine +4

Lowered oesophageal sensory thresholds in patients with symptomatic but not excess gastro-oesophageal reflux: evidence for a spectrum of visceral sensitivity in GORD.

Ken Trimble, A Pryde, R C Heading · Gut · 1995 · 267 citations · Full text