Synthesis of 1‐(2,6‐Dimethylphenyl)‐<i>N</i>‐hydroxy‐4,4‐dialkyl‐2,5‐dioxo‐<i>N</i>‐aryl‐3‐pyrrolidine‐carboxamides from Reaction of 2,6‐Dimethylphenyl Isocyanide, Alkylidene Meldrum's Acids, and Arylhydroxylamines

Abstract

Abstract Alkylidene Meldrum's acids and 2,6‐dimethylphenyl isocyanide react smoothly in the presence of arylhydroxylamines at room temperature to produce 2,5‐dioxo‐pyrrolidines in fairly high yield.