Physical Review Letters · 2009 · 250 citations · 14 references
Public HealthNeuroscienceNeural EngineeringTrauma-related DisordersTraumatic Brain Injury PreventionBlast Injury PreventionHelmet SafetyHelmet UseTrauma BiomechanicsTraumatic Brain InjuryBlast Injury BiomechanicsBlast SimulationBlast-related Traumatic Brain InjuryBrain Injury BiomechanicsBrain Injury CausationBrain Injury MechanicsHead Injury BiomechanicsHydrodynamic Simulations
Traumatic brain injury (TBI) has become a signature injury of current military conflicts, with debilitating, costly, and long-lasting effects. Although mechanisms by which head impacts cause TBI have been well researched, the mechanisms by which blasts cause TBI are not understood. From numerical hydrodynamic simulations, we have discovered that nonlethal blasts can induce sufficient skull flexure to generate potentially damaging loads in the brain, even without a head impact. The possibility that this mechanism may contribute to TBI has implications for injury diagnosis and armor design.
14
Traumatic Brain Injury in the War Zone
Susan Okie · New England Journal of Medicine · 2005 · 768 citations
Ultrastructural and Functional Characteristics of Blast Injury-Induced Neurotrauma
Ibolja Černak, Zhengguo Wang, Jianxin Jiang et al. · 2001 · 373 citations
Pharmacy, Neurobiology, Neuroscience +17