Monitoring impurities in biopharmaceuticals produced by recombinant technology

A dot-immunobinding assay for monoclonal and other antibodies

Richard Hawkes, Evelyn Niday, Julian Gordon · Analytical Biochemistry · 1982 · 2.2K citations

Life Sciences, Biotechnology, Immunology +13

Characterization of PicoGreen Reagent and Development of a Fluorescence-Based Solution Assay for Double-Stranded DNA Quantitation

Victoria L. Singer, Laurie J. Jones, Stephen Yue et al. · Analytical Biochemistry · 1997 · 783 citations

Life Sciences, Biochemistry, Molecular Biology +13

The development of stable protein formulations: a close look at protein aggregation, deamidation, and oxidation.

Jeffrey L. Cleland, Melissa Powell, S J Shire · PubMed · 1993 · 542 citations

Pharmacy, Biochemistry, Pharmaceutics +17

Non-radioactive hybridization probes prepared by the chemical labelling of DNA and RNA with a novel reagent, photobiotin

Anthony Forster, James L. Mclnnes, Derek C. Skingle et al. · Nucleic Acids Research · 1985 · 522 citations · Full text

Life Sciences, Biology, Molecular Biology +11

Cutting out the middleman: DNA biosensors based on electrochemical oxidation

H. Holden Thorp · Trends in biotechnology · 1998 · 255 citations

Engineering, Biotechnology, Molecular Biology +14