Glutamine synthetase mutation conferring target‐site‐based resistance to glufosinate in soybean cell selections

Abstract

Changes in sensitivity to glufosinate have been related to mutations at the binding site of the herbicide on the glutamine synthetase. His(249) is one of the residues implicated in the binding domain for the substrate and inhibitor, and hence the exchange of this residue with tyrosine plays a role in lowering the sensitivity of the mutated enzyme.