Higher Glutamate to Glutamine Ratios in Occipital Regions in Women With Migraine During the Interictal State

Abstract

These findings are consistent with glutamatergic differences in migraine patients during the interictal period compared with healthy controls. We hypothesize that an increased Glu/Gln ratio could arise from neuronal-glial coupling of glutamatergic metabolism differences or an increased neuron/astrocyte ratio in the OC.