Genetic and epigenetic control of UNC5C expression in human renal cell carcinoma

Silencing of the VHL tumor-suppressor gene by DNA methylation in renal carcinoma.

James G. Herman, Farida Latif, Y Weng et al. · Proceedings of the National Academy of Sciences · 1994 · 1.5K citations

Medicine, Genetics, Oncology +17

Inactivation of the CDKN2/p16/MTS1 gene is frequently associated with aberrant DNA methylation in all common human cancers.

James G. Herman, Adrian Merlo, Li Mao et al. · PubMed · 1995 · 1.4K citations

Medicine, Genetics, Oncology +17

A Modified and Improved Method for Bisulphite Based Cytosine Methylation Analysis

Alexander Olek, Joachim Oswald, Jörn Walter · Nucleic Acids Research · 1996 · 374 citations · Full text

Life Sciences, Genetics, Molecular Biology +15

Transformation of follicular lymphoma to diffuse large cell lymphoma is associated with a heterogeneous set of DNA copy number and gene expression alterations

José A. Martinez‐Climent, Ash A. Alizadeh, Richard Segraves et al. · Blood · 2003 · 240 citations

Life Sciences, Genetics, Molecular Genetics +17

Epigenetic inactivation of the RASSF1A 3p21.3 tumor suppressor gene in both clear cell and papillary renal cell carcinoma.

C. O. Morrissey, Alonso Martínez, Malgorzata Zatyka et al. · PubMed · 2001 · 200 citations

Medicine, Genetics, Oncology +17