Sarcoidosis: A Case Presenting with Dysphagia and Dysphonia

Abstract

Case Studies1 February 1967Sarcoidosis: A Case Presenting with Dysphagia and DysphoniaWILLIAM E. HARDY, M.D., HENRY TULGAN, M.D., GERALD HAIDAK, M.D., JOSEPH BUDNITZ, M.D., F.A.C.P.WILLIAM E. HARDY, M.D., HENRY TULGAN, M.D., GERALD HAIDAK, M.D., JOSEPH BUDNITZ, M.D., F.A.C.P.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-66-2-353 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptSarcoidosis is a generalized granulomatous disease of unknown etiology that affects many tissues and is characterized pathologically by epithelioid tubercles with little or no necrosis. Over 90% of cases have pulmonary or mediastinal involvement. Occasionally, the nervous system is affected, but rarely is the gastrointestinal tract diseased (1-4). This paper presents an unusual case of sarcoidosis, involving not only the lungs and the cranial nerves but also the esophagus.CASE REPORTThe patient, a 31-year-old, single, white female clinical psychologist, was admitted to Pittsfield General Hospital on March 20, 1966, with complaints of dysphagia, dysphonia, dizziness, fatigue, and weight loss....References1. MAYOCKBERTRANDMORRISONSCOTT RLPCEJH: Manifestations of sarcoidosis. Analysis of 145 patients, with a review of nine series selected from the literature. Amer. J. Med. 35: 67, 1963. CrossrefMedlineGoogle Scholar2. POLACHEKMATRE AAWJ: Gastrointestinal sarcoidosis. Report of a case involving the esophagus. Amer. J. Dig. Dis. (n.s.) 9: 429, 1964. CrossrefMedlineGoogle Scholar3. ISRAELSONES HLM: Sarcoidosis. Clinical observations on one hundred sixty cases. Arch. Intern. Med. (Chicago) 102: 766, 1958. CrossrefGoogle Scholar4. GENDELYOUNGGREINER BJJMDJ: Sarcoidosis. A review with twenty-four additional cases. Amer. J. Med. 12: 205, 1952. CrossrefMedlineGoogle Scholar5. RICKERCLARK WM: Sarcoidosis. A clinicopathologic review of three hundred cases, including twenty-two autopsies. Amer. J. Clin. Path. 19: 725, 1949. CrossrefMedlineGoogle Scholar6. NATHANNEWMANOCHANERBLUM MHAJGL: Sarcoidosis of the upper intestinal tract. Amer. J. Roentgen. 84: 275, 1965. Google Scholar7. ALLENBATTENJEFFERSON EHJCK: Sarcoidosis of the alimentary tract. Brit. J. Radiol. 29: 56, 1956. CrossrefMedlineGoogle Scholar8. KERLEY P: Sarcoidosis, in Modern Trends in Diagnostic Radiology (First Series), edited by MCLAREN, J. W. Hoeber, New York, 1948, p. 150. Google Scholar9. SIEGELHONDASALIKMENDELOFF CIMJAI: Dysphagia due to granulomatous myositis of the cricopharyngeus muscle; physiological and cineradiographic studies prior to and following successful surgical therapy. Trans. Ass. Amer. Physicians 74: 342, 1961. MedlineGoogle Scholar10. DEVINE KD: Sarcoidosis and sarcoidosis of the larynx. Laryngoscope 75: 533, 1965. CrossrefMedlineGoogle Scholar11. ISRAEL HL: Sarcoidosis. Postgrad. Med. 36: 493, 1964. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Pittsfield, Massachusetts, and Albany, New YorkFrom the Departments of Medicine and Surgery, Pittsfield Affiliated Hospitals, Pittsfield, Mass., and the Department of Postgraduate Medicine, Albany Medical College, Albany, N. Y.Dr. Hardy is a trainee under grant E-1407, U. S. Public Health Service, Washington, D. C.Requests for reprints should be addressed to Henry Tulgan, M.D., East Street Medical Building, Pittsfield, Mass. 01201. 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