Expression of p16 Protein Identifies a Distinct Entity of Tonsillar Carcinomas Associated with Human Papillomavirus

A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4

Manuel Serrano, Gregory J. Hannon, David Beach · Nature · 1993 · 3.7K citations

Life Sciences, Cell Biology, Molecular Biology +17

Evidence for a Causal Association Between Human Papillomavirus and a Subset of Head and Neck Cancers

Maura L. Gillison · JNCI Journal of the National Cancer Institute · 2000 · 3.1K citations

Medicine, Oncology, Pathology +13

A Cell Cycle Regulator Potentially Involved in Genesis of Many Tumor Types

Alexander Kamb, Nelleke A. Gruis, Jane Weaver-Feldhaus et al. · Science · 1994 · 2.8K citations

Life Sciences, Genetics, Molecular Genetics +17

Deletions of the cyclin-dependent kinase-4 inhibitor gene in multiple human cancers

Tsutomu Nobori, Kaoru Miura, David Wu et al. · Nature · 1994 · 1.8K citations

Medicine, Molecular Genetics, Oncology +14

Overexpression of p16INK4A as a specific marker for dysplastic and neoplastic epithelial cells of the cervix uteri

Ruediger Klaes, Tibor Friedrich, Dimitry Spitkovsky et al. · International Journal of Cancer · 2001 · 1K citations · Full text

Medicine, Gynecology, Pathology +17