Concepedia

Targeting antioxidant pathways with ferrocenylated N-heterocyclic carbene supported gold(<scp>i</scp>) complexes in A549 lung cancer cells

Jonathan F. Arambula, Rebecca McCall, K. J. Sidoran, Darren Magda, Nicholas A. Mitchell, Christopher W. Bielawski, V.M. Lynch, J.L. Sessler, Kuppuswamy Arumugam

Chemical Science · 2015 · 99 citations · 88 references

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Concepts

Abstract

Ferrocenylated-Au(<sc>i</sc>) carbenes were designed, synthesized, and studied for their ability to generate reactive oxygen species and target antioxidant pathways<italic>via</italic>multiple mechanisms.

References

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