Palladium‐Catalyzed Allylic Arylation of Allylic Ethers with Arylboronic Acids Using Hydrazone Ligands

Abstract

Abstract Unsymmetrical 1,3‐diarylpropenes were synthesized in good to high yields by the palladium‐catalyzed allylic arylation of allylic ethers, such as a cinnamyl phenyl ether, with a variety of arylboronic acids using a hydrazone 1a –Pd(OAc) 2 system in DMAc/H 2 O. Using this catalyst, eugenol was also synthesized from allyl phenyl ether with (4‐hydroxy‐3‐methoxyphenyl)boronic acid pinacol ester.