Boldine improves endothelial function in diabetic <i>db/db</i> mice through inhibition of angiotensin <scp>II</scp>‐mediated <scp>BMP4</scp>‐oxidative stress cascade

Abstract

Boldine reduced oxidative stress and improved endothelium-dependent relaxation in aortas of diabetic mice largely through inhibiting ROS overproduction associated with Ang II-mediated BMP4-dependent mechanisms.