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New adrenal-scanning agent.
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1975
Year
Possible Adrenal-scanning AgentAdrenal GlandOxysterolBiochemistryTissue Distribution StudiesPhysiologyPharmacologyBioinstrumentationNew Adrenal-scanning AgentNew Adrenal-specific CompoundAdrenal DiseaseClinical ChemistryEndocrinologyMedicineAtherosclerosisSteroid Metabolism
A new adrenal-specific compound, 6beta-iodomethyl-19-norcholest-5(10)-en-3beta-ol(NCL-3-I), which is derived from 19-iodocholesterol (CL-19-I), has been found. Tissue distribution studies have revealed that the rat adrenal gland accumulates ten times more NCL-6-131-I than CL-19-131-I. The advantage of NCL-6-131-I as a possible adrenal-scanning agent is discussed.