CONGENITAL ASYMMETRY: REPORT OF 10 CASES WITH ASSOCIATED DEVELOPMENTAL ABNORMALITIES

Abstract

Ten patients with total congenital asymmetry were found in a review of the charts of some 860,000 admissions to The New York Hospital-Cornell Medical Center over the interval 1932-1966. Associated abnormalities described include two instances of adrenal neoplasm, one case of bilateral medullary sponge kidneys, and a possible case of Beckwith's syndrome. Six of the 10 patients had abnormalities of the genitourinary system. An oncogenic-teratogenic relationship and a possible biologic system for the study of such a relationship are suggested.