Concepedia

Kinetics of P-Glycoprotein-Mediated Efflux of Paclitaxel

Seong H. Jang, M. Guillaume Wientjes, Jessie L.‐S. Au

Journal of Pharmacology and Experimental Therapeutics · 2001 · 124 citations · 24 references

DOI

Concepts

References

24

Mechanism of mitotic block and inhibition of cell proliferation by taxol at low concentrations.

Mary Ann Jordan, Robert Toso, Douglas Thrower et al. · Proceedings of the National Academy of Sciences · 1993 · 1.1K citations · Full text

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Mitotic block induced in HeLa cells by low concentrations of paclitaxel (Taxol) results in abnormal mitotic exit and apoptotic cell death.

M A Jordan, K Wendell, Sheila M. Gardiner et al. · PubMed · 1996 · 783 citations

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Taxol binds to polymerized tubulin in vitro

Jerome Parness, SB Horwitz · The Journal of Cell Biology · 1981 · 620 citations · Full text

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Taxol binds to cellular microtubules.

James J. Manfredi, Jerome Parness, S. B. Horwitz · The Journal of Cell Biology · 1982 · 410 citations · Full text

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Functional expression of P-glycoprotein in apical membranes of human intestinal Caco-2 cells. Kinetics of vinblastine secretion and interaction with modulators

Janice Hunter, Mark A. Jepson, T Tsuruo et al. · Journal of Biological Chemistry · 1993 · 367 citations · Full text

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